ABC of antithrombotic therapy: Valvar heart disease and prosthetic heart valves
نویسندگان
چکیده
منابع مشابه
Antithrombotic Therapy in Patients with Prosthetic Heart Valves
Patients with mechanical valve prostheses require a lifelong anticoagulant treatment. The combined use of Warfarin and low-dose aspirin appears to reduce the risk of valve thrombosis and systemic embolism at a low risk of bleeding. The management of women with prosthetic heart valves during pregnancy poses a particular challenge, as there are no available controlled clinical trials to provide g...
متن کاملAntithrombotic Management of Patients with Prosthetic Heart Valves.
Valvular heart disease is a major public health issue. The prevalence of valvular heart disease is expected to increase due to an aging population. Valve dysfunction manifests as valve stenosis, regurgitation, or both, due to various etiologies. Valve repair and replacement are the main treatment options for severe valve dysfunction. Valve replacement is achieved by using either a mechanical or...
متن کاملAntithrombotic Therapy in Patients With Mechanical and Biological Prosthetic Heart Valves
In 1992, based on extensive review of the literature, we concluded that in patients with mechanical prosthetic heart valves,1 (1) long-term (permanent) therapy with oral anticoagulants offers the most consistent protection, and (2) levels of oral anticoagulants that prolong the prothrombin time (PT) ratio to an international normalized ratio (INR) of 2.5 to 3.5 are satisfactory for tilting disk...
متن کاملAntithrombotic therapy in patients with mechanical and biological prosthetic heart valves.
1. Permanent therapy with oral anticoagulants offers the most consistent protection in patients with mechanical heart valves. 2. Antiplatelet agents alone do not consistently protect patients with mechanical prosthetic heart valves, including patients in sinus rhythm with St. Jude Medical valves in the aortic position. 3. Levels of oral anticoagulants that prolong the INR to 2.0 to 3.0 appear s...
متن کاملProsthetic Aortic Heart Valves
In this review, the anatomy and structure of the aortic valve and its prostheses are comprehensively discussed. Cardiac anatomy and function, human heart valves and their prostheses are also extensively discussed. The current status of prosthetic heart valves along with the next generation of these devices is broadly deliberated. Ather promising options such astranscatheter technologies (percut...
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ژورنال
عنوان ژورنال: BMJ
سال: 2002
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.325.7374.1228